Anatomy and Micromorphology of Inula helenium subsp. orgyalis and I. ensifolia (Asteraceae) from Turkey
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Microwave-assisted Extraction of Alantolactone and Isoalantolactone from Inula helenium
Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium. Effects of various experimental factors including ethanol concentration, particle size, microwave radiation time, the ratio of material to liquid and extraction temperature on yield of alantolactone and isoalantolactone were evaluated. The optimal extracting process of the alanto...
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Eight sesquiterpene lactones were isolated from the roots of Inula helenium and flowers of I. japonica. Among them, isoalantolactone (3) and santamarine (6) exhibited significant growth inhibitory activities against gynecologic cancer cell lines, while others weakly inhibited the growth of the cell lines (IC50 < or = 100 microM). In addition, 3 significantly inhibited the tumour growth of S180 ...
متن کاملThymol derivatives from a root culture of Inula helenium.
A root culture of Inula helenium L. was established from leaf explants of aseptic seedlings. An ethanol extract from the lyophilised roots was fractionated using different chromatographic techniques (CC, TLC). The main secondary metabolites found in the root culture were two thymol derivatives: 10-isobutyryloxy-8,9-epoxy-thymol isobutyrate (1) and 10-isobutyryloxy-6-methoxy-8,9-epoxy-thymol iso...
متن کاملAntiproliferative sesquiterpene lactones from the roots of Inula helenium.
The MeOH extract of the roots of Inula helenium showed a high inhibitory activity for cell growth against MK-1, HeLa and B16F10 cell lines. Significant activity was found in the hexane-soluble fraction. From the hexane-soluble fraction, seven sesquiterpenes, namely, one germacrane (4beta,5alpha-epoxy-1(10),11(13)-germacradiene-8,12-olide), one elemane (igalane), and five eudesmanes (alantolacto...
متن کاملUltrasound-Assisted Extraction of Total Phenolic Compounds from Inula helenium
Ultrasound-assisted extraction (UAE) of phenolic compounds from Inula helenium was studied. Effects of ethanol concentration, ultrasonic time, solid-liquid ratio, and number of extractions were investigated. An orthogonal array was constructed to optimize UAE process. The optimized extraction conditions were as follows: ethanol concentration, 30%; solid-liquid ratio, 1 : 20; number of extractio...
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ژورنال
عنوان ژورنال: Notulae Scientia Biologicae
سال: 2017
ISSN: 2067-3264,2067-3205
DOI: 10.15835/nsb919950